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CBS4 Colorectal Campaign: Viral Infections

Click here for more information on CBS4.COM/Colorectal

MIAMI (CBS4) ― CBS 4 "The Test For Life" campaign stresses the importance of getting tested for colon cancer and you can be tested for free. Colon cancer is the second leading cause of cancer death in the U.S. and with few specific signs or symptoms, the only hope of catching it early is to get screened.

About 150,000 people in the U.S. are diagnosed with cancer of the colon or rectum every year, and about 50,000 will die from the disease. It strikes men and women equally. 

A common virus might be causing some cases of colorectal cancer, which according to Dr. Ekaterina Dadakova from Albert Einstein University, is not at all unusual.

"According to the health statistics, approximately 1.3 million cases of cancer  worldwide are caused by pre-existing viral infections," explained Dr. Dadakova. 

But this virus is the human papilloma virus, or HPV, the same virus well-known to cause cervical cancer in women.

It's believed when HPV infects a cell, and the viral DNA changes the cell's DNA causing it to start dividing irregularly and aggressively. In the early stages, it's called atypia.

But Dr. Henry Wodnicki from Mount Sinai Medical Center says that atypia is how tumors start to grow. 

"With each mutation, the cells tend to become more unusual, more bizarre-looking, and as we were talking about with atypia, it approaches cancer, and eventually it becomes a cancer," said Dr. Wodnicki.

A recent study conducted by the National Cancer Institute found 51% of the colorectal tumors they tested were positive for HPV in both men and women. Other studies have found similar results. And since the virus is sometimes transmitted sexually, particularly in gay men, doctors are beginning to test for it just like they do for cervical cancer.

"What we've been doing is Pap smears on all males who have been exposed, or potentially exposed to HPV," Dr. Wodnicki added.

The good news is if the HPV virus is causing some colon cancers, a vaccine might one-day protect against it.

(© MMVIII, CBS Broadcasting Inc. All Rights Reserved.)


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